BSRT Graduate School


Cardiovascular System


Description: Introduction: What is heart disease, why do we need regenerative medicine - How to diagnose heart disease – visit echo and MRI - How can the cardiologist treat heart disease – visit cath lab - How heart surgery is done – visit OR - Treatment of patients on the ICU – visit ICU - Heart transplantation and mechanical assist devices for heart failure – visit transplant & assist - How to prepare stem cell products for cardiac cell therapy – visit clean room lab - Viable tissues for heart surgery – visit tissue engineering lab - Intrinsic regeneration of the myocardium (Neoangiogenesis, Myocyte mitosis vs. hypertrophy) - Experimental strategies for cell-based cardiac regeneration (library, Skeletal myoblasts, Embryonic stem cells, Bone marrow cells, Neonatal stem cells, Gene therapy) - Clinical cell therapy for heart disease

Advanced Technologies – Pre-Clinical Model Systems


This course offers a 2.5-day advanced training on preclinical animal models.


The course starts with a short discourse on the history of animal experimentation in science, covers regulatory aspects and will introduce the 3Rs principle, which has evolved into 6Rs and could even be extended to 7Rs. Furthermore, animal experimental work will be discussed from an ethical point of view and alternatives to in vivo research will be addressed. New technologies such as the use of genetic modifications and resulting test systems will also be a topic. In this context, the time required to create a transgenic animal model will also be addressed and its advantages and disadvantages discussed. The goal of trying to mirror clinical patient conditions in animal models will be challenged.


The course will include some introductory lectures but aims to engage you in lively discussions stimulated by group exercises.


Skeletal Development - Investigating skeletal development in the mouse


This practical course gives an introduction into the methods and technology used to investigate skeletal and muscle development in the mouse. The skeleton evolves from mesenchymal cells which differentiate into bone forming osteoblasts and cartilage forming chondrocytes. Through a complex genetic program these cells eventually form the mature bone, keep this tissue in homeostasis and provide a cellular resource for healing. Muscles on the other hand form from progenitors arising in the somites, which reach their final destionations via a migration process. During muscle formation a subpopulation of myogenic cells is arrested in the undifferentiatied state and serves as stem cells (so-called satellite cells) for regenerative processes in the adult. In this course, the participants will be able to investigate gene and protein expression during skeletogenesis and myogenesis in the mouse and to analyze skeletal malformations in mouse models for human skeletal disease. This course is aimed at providing a basic understanding for the genetic mechanisms that govern musculoskeletal patterning and differentiation during embryogenesis and to provide knowledge on how to analyze musculoskeletal phenotypes in animal models.


Course Materials and Techniques

The onset of skeletal and myogenic development in the embryo will be analyzed by RNA in-situ hybridisation, the formation of muscles and muscle stem cells will be analized by immunostaining on tissue sections. The differentiation of cartilage and bone will be analyzed by histology of embryonic tissue sections. The patterning and morphogenesis of the skeleton will be analyzed in wild type and mutant mice by whole mount skeletal staining.

Clinical Training - Musculoskeletal Anatomy


During this course the students will be provided with the basic knowledge about the anatomy of the motion apparatus. A lot of examples from orthopedic and traumatologic allday will support the theoretic insight and enable the students to understand clinical problems, evolving around the anatomic field. A workshop, which will take place in the Institute for Anatomy of the Campus Charité Mitte will allow the participants to get in touch with "real" anatomy in form of specimens of extremities and to get a deeper understanding of the acquired knowledge.

Teaching - Student Centered Coaching


This course offers a two-day workshop on student-centered coaching methods. In short seminars, you will learn about problem based learning (PBL) methods and other methods such as Design Thinking that are used to encourage knowledge acquisition and problem solving through group collaboration. You will learn when and why a coach is required and about the different roles a coach can assume. In teamwork, you will design and plan the PBL sessions for the next BSRT course “Introduction into research in regenerative therapies”. You will get hands-on experience in coaching during one PBL session of the follwoing BSRT introduction course under the supervision of Fabian Feutlinske. One PBL session takes usually no more than half a day. During the PBL sessions, you will guide the teams of new doctoral researcher and help them in their transition from students who are used to passively acquire knowledge in lectures and from text books to becoming the next generation of researcher who take matters into their own hands and solve problems independently.



You need to have already participated in the BSRT course “Introduction into research in regenerative therapies”



Fabian Feutlinske has a PhD in Biochemisty and Molecular Biology from the Freie Universität Berlin and several years of coaching experience. He moderated the PBL sessions in the BSRT introduction courses and he has been the BioThinking Coach in various research projects funded by the Einstein Center for Regenerative Therapies.



Two workshop days and one day hands-on experience in the following BSRT course “Introduction into research in regenerative therapies”.

Career Orientation - What Does it Mean To Do a PhD?


What does it mean to do your PhD?

From successful project management to the daily challenges in translational research


In this interactive workshop, we will discuss your expectations for doing a PhD and how to integrate those these expectations into the daily routines at your host institution. Knowing your own goals and the goals and expectations of your team members is key to successful PhD project management. We will discuss the basics of project management and how to:

  • Set realistic milestones for a research project and career development (Phase I)
  • Deal with setbacks, manage frustrating unexpected outcomes, and develop strategies that will make you more resilient (Phase II)
  • Build rewarding collaborations with other researchers on a translational team (Phase III)

Science Communication - Advanced Scientific Drawing



Take a look at benchmarks in Science like Cell- and Nature- Press and realize how much work is dedicated into the visual aspects of high quality publication. In this 2-hour practical course, we will explore and discuss the world of scientific drawing. Visualization of your scientific ideas, biological processes, workflows and data is today a central aspect in scientific communication. May it be your next paper, review, your thesis or your next grant application, all will benefit from thoughtful and aesthetic graphics that facilitate your ideas and work.


We will discuss the basics of scientific drawing and:

  • Compare different graphic software for the creation of individual artwork including CorelDraw, InkScape, PhotoShop and cloud-based solutions such as Biorender
  • Discuss at the example of good and bad artwork which artistic decisions place a scientific message into focus
  • Each participant will use his/her PhD project idea to create an own scientific drawing of high quality that will be presented, discussed and improved over the course


The course is planned to be held in person. If the number of participants is too low, it will be held online.



Statistic - Introductory Biostatistics for Clinical Research - an experiential learning course


Farzad Noubary, Ph.D., Assistant Professor, Tufts University School of Medicine, Senior Statistician, Tufts Medical Center

in collaboration with Professor Mohamed Abou El-Enein, scientific coordinator of the translational track 


Day 1

Session 1 & 2: Basics of research studies, types of data, measures of location and spread, graphics, correlation Session

3 & 4: Basics of probability including conditional probability, diagnostic tests, Bayes Rule; data manipulation in Stata


Day 2

Session 5 & 6: Sampling, discrete densities including the binomial and Poisson distributions, continuous densities including the normal

Session 7 & 8: Expected value, estimation, central limit theorem, confidence intervals


Day 3

Session 9 & 10: Hypothesis tests, p-values, one and two sample comparisons of means

Session 11 & 12: Analysis of variance, F-distribution, multiple testing

Session 13 & 14: Nonparametric tests, permutation tests


Day 4

Session 15 & 16: Inference on proportions

Session 17 & 18: Contingency tables, chi-square test, Fisher’s exact test, paired data

Session 19 & 20: Correlation and introduction to linear regression


Science Communication - How to present a TED like talk


Jochen Müller is a science journalist and moderator as well as trainer for science communication. In a one day workshop, he will coach early career scientists in story telling methods and give presentation training with the goal that participants are able to prepare a TED like talk. After a week, the participants will receive the opportunity to optimise their presentations in a follow up workshop with a feedback round for each presentation (half a day).

Teaching - Student Centered Teaching


Teaching skills get more and more relevant for young researchers who plan their professional future in academia. The BSRT in cooperation with the “Berliner Zentrum für Hochschullehre” offers therefore the workshop:The four-day course will focus on the basics of teaching and learning at universities with a special emphasis on teaching in the biomedical fields.


In this interactive workshop participants will learn how to carry out goal- and audience-oriented teaching, lectures and presentations and practice teaching activities such as articulating learning goals, planning class sessions, and designing assessments. Participants will analyze specific teaching situations and learn to facilitate student learning in different situations. The workshop also provides the opportunity for participants to develop their own course. 


Learning objectives:

  • Participants are able to plan their courses stundent-oriented
  • Participants are able to foster students learning
  • Participants are able to design an appropriate assessment
  • Participants know different parts of the teaching role and are able to choose them adequatly according to the specific teaching situation
  • Participants present complex scientific subjects well structured and clearly.


Who should attend:

This course is suitable for Postdocs with little to no experience in teaching but could also be of interest for more advanced lecturers aiming to refresh or complement their didactic expertise. Advanceds Doctoral students who want to gain some teaching experience at the BSRT are also welcome. A maximum of 14 people can attend.



This course is part of Module 1 of the  Berliner Zentrum für Hochschullehre” and will be accepted for the Habilitation at the Charité.


Language: The workshop language is German, but can be provided in English if required.