BSRT Graduate School

Courses

Stem Cell

8/8
Description:

Inside every stem cell is an organ waiting to happen…” - Eisenstein.M

 

Moving from 2D to 3D cellular systems, we will address in vitro and ex vivo organoid generation techniques discussing their limitations and shedding light on recent advances in the field. We will delve into the wide-ranging applications of organoids in disease modelling, diagnosis and personalized medicine with specific attention to research interest of participants. The course will focus on organoid generation in terms of practical skills as well as basic knowledge on human developmental biology important to set the basis for protocol establishment. Attending this course will equip you with all the theoretical and technical knowledge needed to develop your own organoid protocols and solve the possible difficulties.

 

Duration

The course comprises 2 days where the lectures will be accompanied by hands-on experience on techniques to generate and maintain 3D cell culture models/organoids. Functional assays important to answer specific research questions will be also taken into account. We will adapt the content as much as possible for the participants (tissue of interest) so that each student can have an idea regarding the possibilities of utilizing organoid technology in their own fields/project.

 

Eligibility

This course addresses PhD students who have at least a basic knowledge of stem cells and would like to establish or learn about 3D organoid models.

 

Teaching

8/15
Description:

This course offers a two-day workshop on student-centered coaching methods. In short seminars, you will learn about problem based learning (PBL) methods and other methods such as Design Thinking that are used to encourage knowledge acquisition and problem solving through group collaboration. You will learn when and why a coach is required and about the different roles a coach can assume. In teamwork, you will design and plan the PBL sessions for the next BSRT course “Introduction into research in regenerative therapies”. You will get hands-on experience in coaching during one PBL session of the follwoing BSRT introduction course under the supervision of Fabian Feutlinske. One PBL session takes usually no more than half a day. During the PBL sessions, you will guide the teams of new doctoral researcher and help them in their transition from students who are used to passively acquire knowledge in lectures and from text books to becoming the next generation of researcher who take matters into their own hands and solve problems independently.

 

Requirements

You need to have already participated in the BSRT course “Introduction into research in regenerative therapies”

 

Tutor

Fabian Feutlinske has a PhD in Biochemisty and Molecular Biology from the Freie Universität Berlin and several years of coaching experience. He moderated the PBL sessions in the BSRT introduction courses and he has been the BioThinking Coach in various research projects funded by the Einstein Center for Regenerative Therapies.

 

Duration

Two workshop days and one day hands-on experience in the following BSRT course “Introduction into research in regenerative therapies”.


Statistic

14/20
Description:

Instructor:
Farzad Noubary, Ph.D., Assistant Professor, Tufts University School of Medicine, Senior Statistician, Tufts Medical Center

in collaboration with Professor Mohamed Abou El-Enein, scientific coordinator of the translational track 

 

Day 1

Session 1 & 2: Basics of research studies, types of data, measures of location and spread, graphics, correlation Session

3 & 4: Basics of probability including conditional probability, diagnostic tests, Bayes Rule; data manipulation in Stata

 

Day 2

Session 5 & 6: Sampling, discrete densities including the binomial and Poisson distributions, continuous densities including the normal

Session 7 & 8: Expected value, estimation, central limit theorem, confidence intervals

 

Day 3

Session 9 & 10: Hypothesis tests, p-values, one and two sample comparisons of means

Session 11 & 12: Analysis of variance, F-distribution, multiple testing

Session 13 & 14: Nonparametric tests, permutation tests

 

Day 4

Session 15 & 16: Inference on proportions

Session 17 & 18: Contingency tables, chi-square test, Fisher’s exact test, paired data

Session 19 & 20: Correlation and introduction to linear regression

 

Science Communication

15/15
Description:

The Advanced Scientific Writing Workshop shows you how to organize, structure and write your conference abstracts and research papers effectively and efficiently. How to get started and keep going as well as what goes where and in which tense will be the starting point of this workshop. We will also review key scientific sentence structures as well as strategies to keep your text concise and precise. Issues such as how to create flow and generate the correct level of emphasis will also be discussed. Together we will explore how to make scientific writing understandable and readable and begin the process of integrating these factors into your own scientific writing style. Finally, we will formulate a plan on how you can improve your scientific vocabulary and writing style for future writing tasks.


Histology

12/13
Description:

This theoretical and practical basic histological course is designed for students from all scientific fields with no or just a minimal experience and background in histological analyses. The course will give an overview on the histology of tissue with a special focus on musculoskeletal tissue and its regeneration. Evaluation of tissue processes can be achieved by conventional stainings as well as cell interactions with immunohistological stainings. In lectures, we will teach basic knowledge about tissue anatomy, tissue preparation, different common staining methods as well as the scientific benefit and application possibilities of histological analyses. In the accompanying practical part, we will apply the theoretical knowledge on tissue samples including the tissue embedding process, the preparation of plastic and paraffin sections, different conventional and immunohistological staining procedures, microscopy and histomorphometry. An insight into nanoindentation and confocal microscopy will also be included in the course.

 

Course Materials and Techniques: different tissue samples, tissue handling for histology, basic histological preparation and staining methods, microtome, microscope, histomorphometry, nanoindentation, confocal microscopy
 


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