BSRT Graduate School

Courses

Career Management

13/10
Description:

In the Career Mentoring and Management (CMM): Applying for Jobs on the Wider Market workshop, you will receive comprehensive career advice about the wealth of alternative career paths that are open to you. You will also explore which skills, knowledge and experience, etc. will be needed to better position yourself to obtain your career goals. In addition, the course will also cover how to best find and access these jobs via comprehensive and proactive job searching activities.

 

To better align your unique constellation of skills, knowledge and experience as well as your natural abilities, talents and preferences with your future career path goals, we will work with an Individual Development Plan (IDP). This will allow us to create an inventory of your core competencies, innate abilities and achievements that will act as a guide to help you better decide on, develop and manage your strategic short- and long-term career goals – a prerequisite to better shaping and steering your career path.

 

To be successful on the wider market, you will need outstanding self-marketing skills. You will therefore be armed with key presentation and communication skills such as how to optimally build and present your CV. To this end, we will also work on producing convincing personal career mission statements and strong core competencies summaries. Further, you will also learn how to best present your core competencies, innate abilities and achievements in attention-grabbing application letters. Finally, we will role play, record and analyse common interview questions to ensure that you gain competitive edge over other application candidates.

 

Dates

13 and 14 September 2021: 1.5 day Introductory training

20 and 21 September 2021: 2 x 1 day Follow-up (small groups)


Mechanics

2/4
Description:


The goal of this course is to provide a basic introduction to the Finite Difference Time Domain Method (FDTD) and exemplary applications in quantitative ultrasound bone healing. As the course duration does not allow going into the detailed theory, it is designed as a hands-on training giving participants a chance to use and learn how to operate FDTD software (SimSonic). After a basic overview of the concepts behind FDTD, we will provide introductory training to the software that will be used later on in the course. Starting with simple examples, for which analytical solutions are known (e.g. reflection at boundaries, scattering from a spherical inclusion), will be modeled in order to demonstrate the importance of element choice and mesh refinement. Once these basic ideas are understood we will then approach real bone and cartilage geometries coming from Scanning Acoustic Microscopy (SAM) and microcomputed tomography (µCT) images. These images will be segmented (Matlab), FDTD simulation maps will be produced, mechanical properties will be included and sound propagation and backscattering will be modeled. Moreover, the effects of more detailed material properties, such as inhomogeneity and anisotropy will be investigated and compared with experimental data.

 

Day 1

- Introduction to SimSonic with main emphasis on musculoskeletal ultrasound application

- Hands on demo

- Revision of acoustics, mechanics, introduction to FDTD

 

Day 2

- Simple problems (plate, spherical inclusion) with comparison to analytical solution 

- Effect of element size, sampling rate and other parameters

- From the medical image to the FDTD geometry, simple material properties

- Examples to be modeled > (a) intact long bones, bones with pores > (b) cartilage and soft scaffold

 

Day 3

- Advanced material properties (example a) > material heterogeneity and anisotropy of bone tissue

- Advanced structural properties (example b) > effects of cell morphology and distribution (random vs. layered structure)

- Independent work on an individualized example

- Report preparation

- Free discussion based on topics brought by the students

 

 

Course Materials and Techniques:

- Simsonic, www.simsonic.fr

- E. Bossy, M. Talmant, and P. Laugier. Three-dimensional simulations of ultrasonic axial transmission velocity measurement on cortical bone models. Journal of the Acoustical Society of America, 115(5):2314{2324, 2004. 3

- G C Cohen. Higher-order numerical methods. Springer, Berlin, 2002. 9

- D Royer and E Dieulesaint. Elastic waves in solids I. Springer-Verlag, Berlin, 2 edition, 1999. 4

 


Cell Biology Signaling

9/10
Description:

Goal of this 3 day workshop is to give an introduction into the crossroads of growth factor signalling and mechanobiology in physiology, pathology and regeneration. Theoretical aspects of the workshop will cover basic concepts in cell-sensation of mechanical cues, integration of extracellular matrix biology and external mechanical cues into intracellular signalling (Prof. Petra Knaus, Dr. Christian Hiepen, Dr. Maria Reichenbach) and coupling of mechanobiology with chromatin and gene transcription (Prof. Sigmar Stricker and Prof. Petra Knaus). Practical aspects will highlight technologies to apply and measure cellular forces, to investigate on the cells force sensing machinery, it’s subcellular localization (Dr. Christian Hiepen, Dr. Maria Reichenbach) and in-silico prediction of genes that underly mechano-dependent regulation (Jerome Jatzlau). The students will review and present primary research articles and review that provide state of art data and concepts in mechanobiology and signal transduction. This workshop is particularly suited for students who want to work at the translational interface of physics, bioinformatics and cell biology.

 


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