BSRT Graduate School


Preclinical Studies





The 3R principle (Replacement, Reduction and Refinement of Animal Experiments) is of utmost significance for research with animals and offers great potential for advancement. Design Thinking is a method to facilitate problem-solving and the development of innovative solutions in multi-disciplinary teams.


We invite you to an interactive workshop focusing on the 3Rs. Think about new approaches regarding the 3Rs and figure out why their implementation in your daily research is sometimes challenging. By using Design Thinking methods, you get an unbiased and playful approach to the 3Rs and find creative space to exchange experiences and work on ways to further implement these principles. The course language is English. Ideally, participants in the "Rethink 3R" course have already gained initial experience in the field of 3Rs for finding highly innovative solutions. As a minimum level, participants are expected to read the information material sent out a few days before the course.


This interactive workshop only works with active and motivated participants, as this is essential for the teamwork and its results. Being shy for example is not a problem, but we need you to be engaged in this course. So please be sure you can relate to this if you register to the course.





In this course the basic tools for the description and measurement of mechanical material behaviour will be presented.


Part A, day 1+2:
- Classification of materials (crystalline, amorphous, compounds)
- Intrinsic electromagnetic interactions
- Introduction of a constitutive law
- Stress-strain curves
- Elastic Theory: Hooke's law, Isotropy, Anisotropy, Technical vs. Engineering Constants
- Plastic Deformation: Toughness, Strength
- Viscoelasticity


Part B (seminar), day 3:
- Students will solve basic mechanical problems related to research in regenerative therapies


Course Material and Techniques:
Ashby and Jones, 2005, Engineering Materials volumes 1 and 2, 3rd Ed.

L.D. Landau and E.M. Lifschitz, Theory of Elasticity, Butteworth-Heinemann, 1986. ISBN: 978-0750626330

T.H. Courtney, Mechanical behavior of materials, McGraw-Hill, Singapore 1990.

W.P. Mason, Physical Acoustics and the Properties of Solids, D.Van Nostrand Company, New York, 1958.