|Biocompatibility of Materials||03.09.2018 09:00 - 17:00||N. Ma, W. Wang||HZG Lecture Hall|
|Biocompatibility of Materials||04.09.2018 09:00 - 17:00||N. Ma, W. Wang||HZG Lecture Hall|
|Biocompatibility of Materials||05.09.2018 09:00 - 17:00||N. Ma, W. Wang||HZG Lecture Hall|
|Biocompatibility of Materials||06.09.2018 09:00 - 17:00||N. Ma, W. Wang||HZG Lecture Hall|
|Biocompatibility of Materials||07.09.2018 09:00 - 17:00||N. Ma, W. Wang||HZG Lecture Hall|
There is no such thing as a biocompatible material” (David Williams). This is the harsh truth every scientist and clinician is facing when working with biomaterials. Nonetheless, biomaterials such as implants are indispensable treatment options in a clinical setting. Examples of frequently used biomaterials include suture materials, stents or hip implants. The first generation of biomaterials was utilized to give physical support and/or mechanical stability. More recent materials even aim to guide tissue processes upon implantation to prevent rejection by tissue or even augment tissue healing and/or regeneration. Hence, biomaterials are required to induce as little adverse effects as possible, when in contact with tissues and cells. The course aims to convey a general understanding about tissue-material and cell-material interactions, especially to scientists without a substantial biological background. Thus, a short introduction into the biology of tissues, cells and basic molecular biological methods will be given. In the scope of this course the principles of biocompatibility, including histo-, immuno-, cyto- and hemo-compatibility, will be introduced and mechanisms of the foreign body response will be discussed. In addition we will learn how cells “feel” the material and how the activation of platelets by an implant can lead to its failure. Methods to evaluate different aspects of biocompatibility and biofunctionality of biomaterials will be presented. Theoretical lectures will be supported by practical laboratory sessions to gain hands-on-experience in a biological lab.
The course is based on the Peer-to-peer course "Biomaterial interaction with cells: test regimes in-vitro".
Course Materials and Techniques: A handout for all participants is available