BSRT Graduate School

Thomas Blankenstein's picture
Charité - Universitätsmedizin Berlin
Institute of Immunology

Charité Campus Benjamin Franklin

Hindenburgdamm 30

12200 Berlin


Since 2000

Director of the Institute of Immunology, Charité - Universitätsmedizin Berlin


Since 1993

Research group leader at the Max Delbrück Center for Molecular Medicine (MDC), Berlin

Research Interests: 

Most of the current experimental cancer models do not reflect the pathophysiology of real-life cancer. Cancer usually occurs sporadically and is clonal in origin. Between tumor initiation and progression clinically unapparent pre-malignant cells may persist for years or decades in humans. More recently, mouse models of sporadic cancer have been developed. The mouse germ-line can be engineered with high precision so that defined genes can be switched on and off in the adult organism, ideally in a locally and timely controlled fashion. However, analysis of the immune response against sporadic tumors requires the knowledge of a tumor antigen.


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