Charité Campus Virchow-Klinikum
Augustenburger Platz 1
W2-Professorship "Biological Basis of Musculoskeletal Regeneration" and Principal Investigator at the Berlin-Brandenburg Center for Regenerative Therapies
Research Team Leader "Stimulation of bone healing", Julius Wolff Institute, Charité Berlin
My research focuses on the investigation of materials and factors to stimulated bone formation. To improve materials used for defect filling, the material properties must be analysed. We have established a set-up that allows the quantification of growth factors within the bony grafting materials, the in vitro testing of the effect of the materials on different cell types, and the efficacy testing of the materials in an animal critical size defect model. This approach allows a detailed analysis of existing and newly developed materials. A severe complication in bone healing is osteomyelitis and therefore the group aims to develop a prophylaxis and treatment for this complication. Osteomyelitis can be caused by several different bacteria and thus the correct antibiotic must be chosen for treatment. The combination of the adequate grafting material with a specific antibiotic and the optimal dosage and release will be important for therapy.