Am Mühlenberg 1
Since 03/2014 Associated Investigator at the Berlin-Brandenburg School for Regenerative Therapies Since 2003 Group Leader at Max Planck Institute of Colloids and Interfaces, Department of Biomaterials, Potsdam
Being a physicist and mathematician from education, my research interest was always to use computer models to predict structural changes in materials. A central topic of my research group “mechanobiology” at the MPI is to study processes in living bone, i.e. bone healing, remodeling and mineralization. In particular, my research focuses on the relation between structural changes of bone on different length and time scales caused by these processes and the underlying control by mechanosensitive cells. Since the study of cellular mechano-regulation in living animals is nowadays hardly feasible and in vitro experiments suffer from the unclear influences of the artificial cell environment, in silico experiments offer a complementary approach. In a computer experiment different hypotheses about a cellular mechano-regulation can be tested by comparing the predicted results of the model with experimental data. Another focus of current research is the topology of the osteocyte network, which is probably the “command center” controlling bone remodeling.